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DOM FIGURE S3 Gene expression in hepatocytes from AZD1656 treatments (4-8 weeks).

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posted on 25.06.2020 by Brian Ford, Loranne Agius

Experimental details are as in Fig. 4: mRNA levels of the indicated genes in hepatocytes from 4-week treatments (A-D) or 8-week treatments (E-L) challenged the with substrates indicated for 4h. Means ± SEM, n= 3-5 (A-D), n=4 (E-L), *P< 0.05 vs respective control (5G); # P < 0.05 vs respective untreated (0 mg/kg).

Funding

MICA: Exploring a new perspective on the mechanism of action of Glucokinase Activators in liver, a preclinical study

Medical Research Council

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