Excel file ( .xlsx) 1. Introductory information: This file is organised in nine excel sheets and each one corresponds to the data shown on a Table or Figure of the article. All data shown was collected between the period of November 2014 and May 2015. The key words for describing the data topic are: Bone scaffolds; Polylactic acid (PLA); Fused Filament Fabrication (FFF); Laser cutting; Pore size; Mechanical properties; In vitro Degradation behaviour. 2. Methodological and data specific information: Sheet 1 contains the data of Table 1 (as it is entitled). This data was acquired with two different techniques, gel permeation chromatography (GPC) and differential scanning calorimetry (DSC). DSC was selected due to the information that it provides about the polymer thermal properties such as glass transition temperature (Tg) and melting temperature (Tm) and GPC was used to acquire the weight average molecular weight (Mw) and polydispersity index (PDI). The polymer thermal properties and weight average molecular weight (Mw) were determined throughout the processing stages of the PLA scaffold ( PLA.filament , PLA.Printed and laser.cut.PLA scaffold) to evaluate if there was any polymer degradation due to processing . Regarding the processing of data to get the values shown in Table 1, both Tg and Tm (melting temperature) were obtained from the DSC thermogram and polystyrene (PS) standards were used for determining the weight average molecular weight (Mw) and polydispersity index (PDI). All the information got from DSC analysis is in degrees Celsius and the Mw is given in Dalton (Da) and the PDI does not have units. Sheet 2 contains the raw data for Table 2 shown in the article. Table 2 gives information about the PLA scaffold morphological characterisation. The average value of five measurements +/- standard deviation (SD) of pore size in XY and XZ axes and filament width was obtained from the SEM images (attached pdf file). All measurements are in millimetres. The average scaffold porosity (P) was evaluated by the following P=1-ρ_(scaffold )/ ρ_(material ) , where ρ material is the density of the material of which the scaffold is fabricated (PLA density= 1.24 g/cm3) and ρ scaffold is the apparent density of the scaffold measured by dividing the weight by the volume of the scaffold. Sheet 3 , contains the data for Figure 5 and 6. In the article, Figure 5 is a stress-strain curve representing the typical behaviour of the PLA scaffold during compression. This specific curve was selected from the group of five replicates (I to V) obtained during compression test. Therefore in this sheet, the data of the five replicates is shown in the form of points (stress and strain columns) and it is also plotted. Additionally the values of stress at yield and compressive modulus, which are obtained from the stress strain curves, are shown. The average values of stress and yield and compressive modulus +/- SD are shown in Figure 6. The compression modulus was calculated from the stress-strain curve as the slope of the initial linear portion of the curve. Compressive strength at yield was determined from the first point on the stress-strain curve at which an increase in strain was observed without an increase in stress. All values are shown in MPa. Sheet 4, contains the raw data for Figure 6.A- B. In the article, Figure 6.A-B is represented by two column charts with the average values +/- SD of stress at yield and compressive modulus of 3 different groups. The raw data of the group entitled “Printed and laser cut PLA scaffold” was already presented in sheet 3. Therefore here it is shown the raw data for the group entitled “Dense PLA”. All the results were obtained as described in sheet 3. The five replicates of “Dense PLA” group were named I-V. Sheet 5, contains the raw data for Figure 6.A- B, more specifically the data of the third group entitled “Printed PLA” with five replicates named A-E. All the results were obtained as described in sheet 3. Sheet 6, contains the raw data for Figure 7, which represents the weekly pH value of the PBS solution during the 8 weeks in vitro degradation study of the PLA scaffolds. The pH was measured to weekly because when PLA degradation occurs, the surrounding environment gets acidic. Thus, measuring the pH was just one way of tracking the degradation process. Sheet 7 and 8, contains the raw data for Figure 8.A and B of the article. These results were acquired from compression testing of PLA scaffolds during the in vitro degradation study, each two weeks. For each time point (0, 2, 4, 6 and 8 weeks), 3 scaffolds were removed from the PBS solution and were tested (n=3). As explained before (sheet 3), after a compression test the resulting data are stress and strain data points, which can be plotted into stress-strain curves and from there you can get the stress at yield and compressive modulus. Figure 8.A-B is represented by two column charts with the average values +/- SD of both stress at yield and compressive modulus for the different time points. Therefore, in sheet 7, the stress-strain data points are shown for week 2 (A1-A3), week 4 (B1-B3), week 6 (C1-C3) and week 8 (D1-D3). Moreover in sheet 8, the stress at yield (MPa) and compressive modulus (MPa) for each time point with the respective replicates (n=3) are shown. Finally the average values +/- SD showed in the column charts of Figure 8.A-B were calculated and are also shown in sheet 8. Sheet 9, contains the raw data for Figure 8.C in the article. Figure 8.C shows the average values of Average Molecular Weight (Mw) +/- SD for each time point (0,2,4,6 and 8 weeks), acquired during the in vitro degradation study. As 3 replicates were run for each time point, in this excel sheet, the Mw of all replicates is shown. PDF file 1. Introductory information: This file shows the 2 scanning electron microscopy (SEM) images shown in Figure 4.A-B. This data was acquired on the 7th of June 2015. The key words for describing the data topic are: PLA scaffolds; morphological characterisation, Top and cross section; SEM. 2. Methodological information: both images were collected with a scanning electron microscopy (SEM) with 30x and 40x magnification in order to have the scaffold morphological characterisation from both top and middle of the structure. These pictures were acquired for measuring the scaffolds features, such as pore size and filament width, which are shown in the excel file explained before.