Data supporting publication: The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse- a model for GCKR rs1260326
Posted on 2023-05-09 - 09:34 authored by Brian Ford
Raw data for "The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse- a model for GCKR rs1260326" published with Molecular Metabolism.
PMID: 37031802.
GEO Accessions:
GSE228696 Short-term effects of overexpression of GK and/or GKRP on the transcriptome in mouse primary hepatocytes (n=36)
GSE228697 Liver transcriptome of GCKR-P446L-EMI-B6N male and female mice (n=18)
GSE228698 Transcriptome of GCKR-P446L-EMI-B6N on a high-fat high-sugar diet (n=56)
CITE THIS COLLECTION
Ford, Brian; Agius, Loranne; Chachra, Shruti; Rodgers, Katrina; Anstee, Quentin; Moonira, Tabssum; et al. (2023). Data supporting publication: The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse- a model for GCKR rs1260326. Newcastle University. Collection. https://doi.org/10.25405/data.ncl.c.6458287.v2
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FUNDING
MICA: Exploring a new perspective on the mechanism of action of Glucokinase Activators in liver, a preclinical study
Medical Research Council
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AUTHORS (12)
SC
Shruti Chachra
KR
Katrina Rodgers
QA
Quentin Anstee
TM
Tabssum Moonira
ZA
Ziad H. Al-Oanzi
HR
Helen L. Reeves
JS
Jörn M. Schattenberg
RJ
Rebecca J. Fairclough
DS
David Smith
DT
Dina Tiniakos