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Data supporting publication: The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse- a model for GCKR rs1260326

Posted on 2023-05-09 - 09:34 authored by Brian Ford

Raw data for "The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse- a model for GCKR rs1260326" published with Molecular Metabolism.


PMID: 37031802.


GEO Accessions:

GSE228696 Short-term effects of overexpression of GK and/or GKRP on the transcriptome in mouse primary hepatocytes (n=36)

GSE228697 Liver transcriptome of GCKR-P446L-EMI-B6N male and female mice (n=18)

GSE228698 Transcriptome of GCKR-P446L-EMI-B6N on a high-fat high-sugar diet (n=56)


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MICA: Exploring a new perspective on the mechanism of action of Glucokinase Activators in liver, a preclinical study

Medical Research Council

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Newcastle University

AUTHORS (12)

Shruti Chachra
Katrina Rodgers
Quentin Anstee
Tabssum Moonira
Ziad H. Al-Oanzi
Helen L. Reeves
Jörn M. Schattenberg
Rebecca J. Fairclough
David Smith
Dina Tiniakos
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