L-arginine in Mitochondrial Encephalopathy, Lactic acidosis, and Stroke-like episodes: A Systematic Review

<p><b>eSupplementary files:</b></p><p>e1. Search strategy</p><p>eFigure 1. Number of patients evaluated for safety and efficacy in Koga et al. 2018</p><p>eReferences</p><p>eTable 2. Excluded studies after full-text review</p><p>eTable3. Summary characteristics of included case reports and cohort study (N=34)</p><p>eTable4. Summary characteristics of included open-label trials (N=3)</p><p>eTable 5. Quality appraisal of case reports and case series </p><p>eTable 6. Quality appraisal for all other non-randomised controlled trials</p><p>eTable 7. PRISMA 2002 Checklist </p><p>eTable 8. PRISMA 2020 for Abstracts Checklist </p><p>eTable 9. PRISMA-S Checklist </p><p> </p><p><b>Raw data files:</b></p><p>Summary data</p><p>Clinical features</p><p> </p><p>Acute response</p>