L-arginine in Mitochondrial Encephalopathy, Lactic acidosis, and Stroke-like episodes: A Systematic Review

eSupplementary files:

e1. Search strategy

eFigure 1. Number of patients evaluated for safety and efficacy in Koga et al. 2018

eReferences

eTable 2. Excluded studies after full-text review

eTable3. Summary characteristics of included case reports and cohort study (N=34)

eTable4. Summary characteristics of included open-label trials (N=3)

eTable 5. Quality appraisal of case reports and case series

eTable 6. Quality appraisal for all other non-randomised controlled trials

eTable 7. PRISMA 2002 Checklist

eTable 8. PRISMA 2020 for Abstracts Checklist

eTable 9. PRISMA-S Checklist

Raw data files:

Summary data

Clinical features

Acute response