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Closed-loop optogenetic control of neural network dynamics

dataset
posted on 2022-04-05, 14:41 authored by Boubker Zaaimi, Mark Turnbull, Anupam Hazra, Yujiang WangYujiang Wang, Carolina Roas, Faye Mcleod, Elaine Mcdermott, Enrique Escobedo-Cousin, Ahmad Shah IdilAhmad Shah Idil, Richard Bailey, Sabrina Tardio, Aaliyah Patel, Johannes Gausden, Nikhil Ponon, Johannes Gausden, Darren Walsh, Frances HutchingsFrances Hutchings, Marcus Kaiser, Mark Cunningham, Gavin Clowry, Fiona Lebeau, Timothy ConstandinouTimothy Constandinou, Stuart BakerStuart Baker, Nick DonaldsonNick Donaldson, Patrick Degenaar, Anthony O'Neill, Andrew Trevelyan, Andrew JacksonAndrew Jackson
Datasets and model accompanying Zaaimi et al.,

Closed-loop optogenetic control of neural network dynamics (Nat Biomed Eng 2022).


Dataset 1 - Closed-loop stimulation of EMX-ChR2 slices (No seizures)


Dataset 2 - Closed-loop stimulation of NHP in vivo (no seizures)


Dataset 3 - Closed-loop stimulation of EMX-ChR2 slices (seizures)


Dataset 4 - Closed-loop stimulation of NHP in vivo (seizures)


CLOSe_model - Closed-loop stimulation of Wilson-Cowan neural mass model

Funding

Wellcome Trust (102037)

EPSRC (A000026)

Wellcome Trust (106149)

History

UoA

  • Psychology, Psychiatry and Neuroscience

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