BP Figure-2: Effects of a high-fat diet on blood lipids and liver GK activity.

P446L mice of the PP or PL genotypes (n=7,7) were fed on either regular diet (RD, open bar) or the high-fat diet (HFD, hashed) for 2 wk. A) Increase in epididymal fat pad mass on the HFD. B) Increase in blood triglyceride and cholesterol and increase in liver GK activity in PL mice on the HFD. *P < 0.05 effect of diet; #P < 0.05 effect of genotype.