10.25405/data.ncl.12550508.v1 Brian Ford Brian Ford Loranne Agius Loranne Agius DOM FIGURE 1 Effect of single exposure to AZD1656 or PF-04991532 on blood glucose and insulin and liver gene expression. Newcastle University 2020 AZD 1656 PF-04991532 GKA C57/BL 6 mouse Cell Metabolism 2020-06-25 09:36:46 Dataset https://data.ncl.ac.uk/articles/dataset/DOM_FIGURE_1_Effect_of_single_exposure_to_AZD1656_or_PF-04991532_on_blood_glucose_and_insulin_and_liver_gene_expression_/12550508 <div><div><div><p>Male C57BL/6 mice were treated with vehicle or AZD1656 (A,E) at the doses indicated 2h before an oral glucose tolerance test or with PF-04991532 (B,F) 1h before the oral glucose tolerance test. C,G. Changes in blood glucose (C) and insulin (G) after treatment with AZD1656 or PF-04991532 before glucose gavage. D. Blood glucose, area under the curve. H. Plasma insulin, area under the curve. I. Liver mRNA levels for the indicated genes normalized to TATA-Binding Protein (TBP) and to vehicle controls. Means ± SEM, n=8, * P < 0.05 relative to vehicle, except for C,G relative to time zero.</p></div></div></div>